What is monopropylene glycol? , Chemistry Blog

Close up of a woman inhaling from an e-cigarette

monopropylene glycol , also known as propylene , Is a viscous, colorless liquid with a characteristic sweet taste (but please do not drink it). Almost odorless, it is miscible with both water and hygroscopic, that is, it attracts and absorbs moisture.

The chemical formula for monopropylene glycol is C. Is3h8hey2Which can also be written as:

Chieftain3CH (OH) CH2Oh

This formula tells us that it has two alcohol groups, making it a diol. its arranged IUPAC Hence the name propane-1,2-diol. Monopropylene glycol has the following physical properties:

  • molecular mass: 76.095 g mol−1
  • Exact Mass: 76.052429 g/mol
  • Flash point: 98.9 °C
  • Boiling Point: 188.2 °C
  • Melting Point / Freezing Point Threshold: -59 °C
  • vapor pressure: 0.13 mm Hg at 25 °C
  • density: 1.0361 g/cubic cm at 20 °C.

What is monopropylene glycol used for?

From antifreeze to food additives, monopropylene glycol There is a wide range of industrial and commercial applications. Some of the most common uses are given below.

  1. polymer
    About 45% of the industrial use of propylene glycol is in the manufacture of various polyester products. It is used as a chemical feedstock in the mass production of unsaturated polyester resins, which are converted into thermoset plastics. During this process, unsaturated maleic anhydride is mixed with isophthalic acid to form copolymers. The partially unsaturated copolymer then undergoes further crosslinking. Meanwhile, propylene glycol reacts with propylene oxide to produce oligomers and polymers, which are then used to make polyurethane.
  2. food additives
    Monopropylene glycol is considered safe for consumption due to its low toxicity, especially in small concentrations. As a result, it is often used as an additive in various food and beverage products, including coffee-based drinks, ice cream, soda, and whipped cream.
  3. pharmaceutical products
    Many types of pharmaceutical and personal care products contain monopropylene glycol. For example, it is a common ingredient in alcohol-based sanitizers, as it helps prevent drying of the skin.
    Monopropylene glycol used as an additive in coffee-based beverages

    Monopropylene glycol is also used as a solvent in some oral, injectable and topical medications. Capable of dissolving drugs insoluble in water, it serves as a good solvent and carrier for drugs such as benzodiazepine tablets.

  4. antifreeze
    A man pours blue antifreeze into a car engine for a window screen.Monopropylene glycol’s low freezing point and high boiling point make it a good antifreeze and coolant, respectively. When mixed with water in a 50% solution, monopropylene glycol significantly lowers the freezing point of water and prevents ice crystals from forming in cold weather. As a result, it is commonly used to de-ice aircraft prior to take-off.
  5. e cigarette
    Monopropylene glycol is one of the main ingredients in the liquid found in electronic cigarettes. Close up of woman breathing e-cigaretteThe heat caused by inhalation vaporizes the chemicals contained in the liquid, creating e-cigarette ‘smoke’.

Is Monopropylene Glycol Safe?

monopropylene glycol is listed under CAS Number: 57-55-6, It is not classified as a significant hazard to health and is considered safe enough to be used as an additive in food and medicines. It is also safe to transport and does not ignite easily.

However, like many other substances, the risk of toxicity increases as the concentration increases. Normally, monopropylene glycol becomes 18 mg/dL. toxic at levels aboveHowever it can vary depending on a person’s body weight, age and health condition.

Propylene Glycol vs Monopropylene Glycol

propylene glycol Monopropylene glycol is synonymous with and interchangeable. So is there any difference? In short, no. They are alternative names for the same chemical compound that contains an alcohol group and a propyl group.

The systematic IUPAC name of this chemical is propane-1,2-diol. Monopropylene glycol/propylene glycol may also be called:

  • α-Propylene Glycol
  • 1,2-propanediol
  • 1,2-dihydroxypropane
  • Methyl Ethyl Glycol
  • methylene glycol

The use of monopropylene glycol in medicine

Monopropylene glycol is mainly used as a solvent and carrier in medicine and other pharmaceutical products. Its miscibility with water means that it can dissolve drugs that are insoluble in water.

Another benefit of monopropylene glycol is that it can prevent drying of topical medications, such as creams and ointments. Thanks to its hygroscopic properties, it can also help keep the skin moisturized.

Monopropylene Glycol MSDS

Material Safety Data Sheet (MSDS) for Monopropylene Glycol Contains a description of first aid measures in case of emergency, along with useful information about the toxicity and dangers of this popular solvent.

It can also include other important details, such as concentration. All material safety data sheets for the chemicals we supply are available to download from our website,

If you are looking for a business Buy high quality monopropylene glycol, visit our online shop today. Available in various batch sizes, ranging from 2.5 Ltrs to 200 Ltrs Drums, you are sure to find the right solution for your needs. And if you need any help, just keep in touch With our friendly customer service team.

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