Blog – Sri Lankan Folk Medicine Can Save Lives

Blog - Sri Lankan Folk Medicine Can Save Lives

A terpene-filled plant, Plectranthus zeylanicus benth can be found growing in the hills of Sri Lanka and is used in Sri Lankan folk medicine as a treatment for inflammation and microbial infections. A team of international researchers is working to isolate the bioactive ingredients of this plant.

Previous investigations have found potent 5-LO inhibitory activity in the lipophilic extract of P. zeylanicus, which supports the anti-inflammatory potential of the plant. In recent work, scientists continue to investigate the anti-microbial properties of various plant extracts and pinpoint the plant’s bioactive secondary metabolites.

A dichloromethane (DCM) extract subjected to bioactivity-guided fractionation yields 7╬▒-acetoxy-6╬▓-hydroxyaroylanone. The compound displayed potent antibacterial activity against antibiotic-resistant Staphylococcus aureus and showed general disinfectant properties similar to those of commercially available disinfectants.

To determine the anti-inflammatory properties of the extract, human blood from volunteers was treated with the test compounds and subjected to SPE cleaning. UCT Products CEC18113 and analyzed using reverse-phase HPLC.

to read the full paper Plectranthus zeylanicus: a rich source of secondary metabolites with antimicrobial, disinfectant and anti-inflammatory activitiesPlease click Here, The article is open access.

Source:

Napagoda, M.; Gerstmeier, J.; Butschek, H.; Lorenz, S.; De Soyza, S.; Kader, M.; Nagahawte, A.; Vijayratne, GB; Schneider, B.; Swat, A.; Jaisinghe, L.; Koeberle, A.; Werz, O. plectranthus zeylanicus: a rich source of secondary metabolites with antimicrobial, disinfectant and anti-inflammatory activities. medicines 2022,

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